NeurosciencebioRxivPreprint
The CYP27A1 - VDR Feedback Rheostat Controls Mitochondrial Protein Homeostasis and Preserves Hippocampal - Striatal Network Integrity to rescue Cognitive impairment in HD condition
Vaishali Kumar, Pradeep Kodam, Chaitanya Kunja…·Shuvadeep Maity
This study identifies a VD-CYP27A1 feedback loop that improves mitochondrial function and rescues cognitive deficits in HD models.
DOI 10.64898/2026.06.11.731670