Author

Sarah M. Broas

University of RochesterORCID 0009-0002-7147-6383Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Organism:E. coli· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Jennifer R. HryhorenkoiD· 2 shared Kevin A. WelleiD· 2 shared Kyle SwovickiD· 2 shared Margaret HoareiD· 2 shared Sina GhaemmaghamiiD· 2 shared Abigail L. BuchwalteriD· 1 shared Andrei SeluanoviD· 1 shared Fatemeh Alimohammadi· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersBiochemistry

Jennifer R. HryhorenkoORCID

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2 papers

Recent·Most cited

BiochemistryProceedings of the National Academy of SciencesPeer-reviewedNov 5, 2024

Formylation facilitates the reduction of oxidized initiator methionines

Ruiyue Tan, Margaret Hoare, Philip M. Bellomio…·Sina Ghaemmaghami

This study shows that formylation of initiator methionines enhances their enzymatic reduction and mitigates oxidation-related misprocessing.

9 citations

E. coliproteomics

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BiochemistryMolecular & Cellular ProteomicsPeer-reviewedMay 24, 2024

Proteome birthdating reveals age-selectivity of protein ubiquitination

Michael E. Meadow, Sarah M. Broas, Margaret Hoare…·Sina Ghaemmaghami

This study introduces proteome birthdating to measure protein age and finds that ubiquitinated proteins are predominantly newly synthesized, with distinct age distributions across cellular pathways.

13 citations

humanproteomics

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