MicrobiologyJournal of Structural Biology XPeer-reviewed
Alanine-scanning of the yeast killer toxin K2 reveals key residues for activity, gain-of-function variants, and supports prediction of precursor processing and 3D structure.
Rianne C. Prins, Tycho Marinus, Eyal Dafni…·Sonja Billerbeck
This study uses alanine scanning and computational methods to map sequence-function relationships in the yeast killer toxin K2, revealing key residues for activity and enabling engineering of enhanced toxicity and specificity.
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