Author

Changyu Zheng

National Institutes of HealthORCID 0009-0002-7634-8516Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Changyu Zheng1 paper · Beijing Normal-Hong Kong Baptist University

Biology Disciplines

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Cell Biology· 1 Genomics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Assay:ATAC-seq· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

John A. ChioriniiD· 2 shared Abhishek TanwariD· 1 shared Blake M. WarneriD· 1 shared Daniel Martı́niD· 1 shared Drew G. MichaeliD· 1 shared Giovanni Di PasqualeiD· 1 shared Hongen Yin· 1 shared Indu Suresh AmbudkariD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersGenomics

John A. ChioriniORCID

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3 papers

Recent·Most cited

ZBTB7B is a Master Regulator of Salivary Acinar Cell Function

Thomas J. F. Pranzatelli, Paola Pérez, Drew G. Michael, Kalie Dominick, Melanie S. Vacchio, Changyu Zheng, Daniel Martı́n, NIDCR/NIDCD Genomics and Computational Biology Core, Philip L. F. Johnson, Blake M. Warner, John A. Chiorini

The paper identifies ZBTB7B as a master regulator of salivary acinar cell function through transcriptional and regulatory analyses in human and mouse salivary glands.

bioRxiv · Oct 16, 2026 · PreprintGenomics

TRPM2 couples cell-autonomous type-I interferon signaling to pigmentation homeostasis

Nutan Sharma, Abhishek Tanwar, Changyu Zheng, Indu Suresh Ambudkar, Rajender K. Motiani

This study identifies TRPM2 as a suppressor of pigmentation through type-I interferon signaling in melanocytes, revealing a novel signaling axis linking immune surveillance to pigmentation homeostasis.

Journal of Biological Chemistry · Oct 1, 2026Peer-reviewedCell Biology

Intranasal AAV Vaccination of SARS-CoV-2 Induce Strong and Sustained Neutralizing Antibodies in Mice

Youngmi Ji, Giovanni Di Pasquale, Changyu Zheng, Sandra A. Afione, Thomas Esperanza, Hongen Yin, Peter D. Burbelo, John A. Chiorini

This study shows that intranasal AAV vaccination in mice generates strong and sustained neutralizing antibodies against SARS-CoV-2 for over a year.

bioRxiv · Mar 14, 2025 · PreprintImmunology