Author

Nutan Sharma

Regional Centre for BiotechnologyORCID 0009-0004-9832-4464Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Rajender K. MotianiiD· 2 shared Abhishek TanwariD· 1 shared Akshay SharmaiD· 1 shared Anushka AgrawaliD· 1 shared Changyu ZhengiD· 1 shared Deepika PandhiiD· 1 shared Divya Bhalla· 1 shared Gyan RanjaniD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCell Biology

Rajender K. MotianiORCID

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2 papers

Recent·Most cited

Cell BiologyJournal of Biological ChemistryPeer-reviewedOct 1, 2026

TRPM2 couples cell-autonomous type-I interferon signaling to pigmentation homeostasis

Nutan Sharma, Abhishek Tanwar, Changyu Zheng…·Rajender K. Motiani

This study identifies TRPM2 as a suppressor of pigmentation through type-I interferon signaling in melanocytes, revealing a novel signaling axis linking immune surveillance to pigmentation homeostasis.

DOI 10.1016/j.jbc.2026.113624

zebrafishmouse

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Cell BiologyCell CalciumPeer-reviewedSep 24, 2026

SERCA2b loss of function drives pigmentation by inducing adaptive ER stress and enhancing mitochondrial calcium uptake: significance in pathological hyperpigmentation associated with Darier’s Disease

Akshay Sharma, Suman Saurav, Preity Sharma…·Rajender K. Motiani

This study identifies SERCA2b as a negative regulator of pigmentation through ER stress and mitochondrial calcium uptake, linking its loss to hyperpigmentation in Darier’s Disease.

DOI 10.1016/j.ceca.2026.103199

humanexperimental assay

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