Author

Julia C. McBride

Brigham and Women's HospitalORCID 0009-0002-7651-7957Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Research Focus:synaptic & neural circuits· 1

Frequent Co-Authors

Mei Yuk Choi· 1 shared Stephen Joseph ElledgeiD· 1 shared Timothy D. MartiniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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3 top collaborators · 3 mutual co-author links

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1 shared paperCancer Biology

Mei Yuk Choi

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1 paper

Recent·Most cited

Cancer BiologyProceedings of the National Academy of SciencesPeer-reviewedSep 2, 2026

Changes in the Transcriptome and Synthetic Lethal Dependencies Following KRAS Mutant Expression Reveal Profound Tissue-Specificity

Timothy D. Martin, Mei Yuk Choi, Julia C. McBride, Stephen Joseph Elledge

This paper identifies tissue-specific synthetic lethal dependencies driven by KRAS mutations across different cell lineages, revealing distinct genetic vulnerabilities shaped by the tissue context.

1 citation

humanbulk RNA-seq

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