Author

Maurizio Toft

Centre National de la Recherche ScientifiqueORCID 0009-0002-7653-1898Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Emmanuel DevaliD· 2 shared Éric LinguegliaiD· 2 shared Ariane DelrocqiD· 1 shared Cédric ValléeiD· 1 shared Emmanuel BourinetiD· 1 shared Frédéric BrauiD· 1 shared Hélène Lubrano Di ScampamorteiD· 1 shared Kévin DelanoeiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersPharmacology & Toxicology

Emmanuel DevalORCID

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2 papers

Recent·Most cited

Short RFamide and CFamide peptides as novel positive modulators of Acid-Sensing Ion Channel 3 with similar potentiating effects but different reversibility

Maurizio Toft, Maëva Meynier, Hélène Lubrano Di Scampamorte, Cédric Vallée, Miguel Salinas, Peijun Zhang, Emmanuel Bourinet, Éric Lingueglia, Emmanuel Deval

The paper identifies two synthetic peptides that potently and selectively modulate ASIC3 activity, showing similar effects but differing in washout kinetics.

bioRxiv · Jul 16, 2025 · PreprintPharmacology & Toxicology

Involvement of ASIC1a channels in the spinal processing of pain information by deep projection neurons

Magda Chafaï, Ariane Delrocq, Perrine Inquimbert, Ludivine Pidoux, Kévin Delanoe, Maurizio Toft, Frédéric Brau, Éric Lingueglia, Romain Veltz, Emmanuel Deval

This study shows ASIC1a/ASIC2 channels in spinal neurons contribute to pain processing by modulating windup through calcium-dependent mechanisms.

PLoS Computational Biology · Apr 17, 2023Peer-reviewedNeuroscience