Author
Koch Institute for Integrative Cancer Research At MITORCID 0009-0002-7734-0567Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Parisa Yousefpour, Justin R. Gregory, Kristen Si…·Darrell J. Irvine
This paper designs a drug-regulated gene expression system using self-amplifying RNA with TMP-responsive degradation domains, showing enhanced immune responses in mice.
Maureen Buckley, Mariluz Araínga, Laura Maiorino…·Darrell J. Irvine
This study visualizes lipid nanoparticle trafficking in non-human primates using PET imaging, showing distribution to muscle and draining lymph nodes with uptake by antigen-presenting cells.
Parisa Yousefpour, Yiming J. Zhang, Laura Maiorino…·Darrell J. Irvine
This study compares the immune response in non-human primates between alum and SMNP adjuvants, finding SMNP induces stronger humoral responses and enhanced lymph node activation.