Mariluz Araínga

A Tissue Virus Microenvironment with Activated Stress Responses Underlies Durable SIV Persistence

This study identifies a tissue virus microenvironment with stress responses that supports SIV persistence, contrasting with transient reservoirs that show immune activity.

Type I IFN reprograms CD4⁺ T cell lipid metabolism as an antiviral effector mechanism during acute HIV/SIV infection

The paper investigates how type I IFN reprograms CD4⁺ T cell lipid metabolism during acute HIV/SIV infection and identifies metabolic changes linked to viral reservoir establishment.

Visualizing lipid nanoparticle trafficking for mRNA vaccine delivery in non-human primates

This study visualizes lipid nanoparticle trafficking in non-human primates using PET imaging, showing distribution to muscle and draining lymph nodes with uptake by antigen-presenting cells.