Author

Kristen Si

Koch Institute for Integrative Cancer Research At MIT

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Amir LedbetteriD· 1 shared Ashley A. LemniosiD· 1 shared Darrell J. IrvineiD· 1 shared Jan LonzarićiD· 1 shared Jonathan DyeiD· 1 shared Junmin WangiD· 1 shared Justin R. GregoryiD· 1 shared Kashif QureshiiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBioengineering

Amir LedbetterORCID

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1 paper

Recent·Most cited

Engineering gene expression dynamics via self-amplifying RNA with drug-responsive non-structural proteins

Parisa Yousefpour, Justin R. Gregory, Kristen Si, Jan Lonzarić, Yingzhong Li, Junmin Wang, Kashif Qureshi, Amir Ledbetter, Ashley A. Lemnios, Jonathan Dye, Tanaka K. Remba, Rachel Yeung, Melissa Güereca, Linette Rodriguez, Yuebao Zhang, , Darrell J. Irvine

This paper designs a drug-regulated gene expression system using self-amplifying RNA with TMP-responsive degradation domains, showing enhanced immune responses in mice.

bioRxiv · Jun 8, 2025 · PreprintBioengineering