Author

Swen Besselink

Radboud University NijmegenORCID 0009-0002-7815-0132Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Anna E. ChristensoniD· 1 shared Bruce R. ConkliniD· 1 shared Carolyn D. Nguyen· 1 shared Da Zhuan XuiD· 1 shared Gokul N. RamadossiD· 1 shared Izaiah J. OrnelasiD· 1 shared James K. NuñeziD· 1 shared Jinna I. BrimiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperGenetics

Anna E. ChristensonORCID

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1 paper

Recent·Most cited

GeneticsNature CommunicationsPeer-reviewedAug 26, 2025

Programmable epigenome editing by transient delivery of CRISPR epigenome editor ribonucleoproteins

Da Zhuan Xu, Swen Besselink, Gokul N. Ramadoss…·James K. Nuñez

This paper introduces RENDER, a method for transient delivery of CRISPR-based epigenome editors as ribonucleoproteins to modulate gene expression in human cells, achieving durable epigenetic silencing.

52 citationstop 1%

humanCRISPR screen

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