Author
University of California, BerkeleyORCID 0000-0002-1157-3168Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Nikita S. Divekar, Ngan Phan, Luis G Palma…·James K. Nuñez
The paper shows RNA m6A modifications coordinate with de novo DNA methylation to establish heritable epigenetic silencing in human cells.
Anna E. Christenson, Nikita S. Divekar, Justin P. Lubin…·James K. Nuñez
LEMONmethyl-seq profiles DNA methylation dynamics in mammalian cells, revealing CRISPR-induced changes and endogenous patterns, including non-canonical CpH methylation.
Da Zhuan Xu, Swen Besselink, Gokul N. Ramadoss…·James K. Nuñez
This paper introduces RENDER, a method for transient delivery of CRISPR-based epigenome editors as ribonucleoproteins to modulate gene expression in human cells, achieving durable epigenetic silencing.
Zena D. Jensvold, Julia R. Flood, Anna E. Christenson, Peter W. Lewis
This study identifies a second HuSH complex, HuSH2, and shows its role in LINE-1 element silencing through interactions with MPP8 and expression dynamics.