Author

Sana Khalili

University of South CarolinaORCID 0009-0002-8635-1540Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:drug response / drug discovery· 2 Research Focus:gene regulatory network inference· 2 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Phillip BuckhaultsiD· 3 shared Carolyn E. BanisteriD· 2 shared Sidney E. Morrison· 2 shared Ashley L. CookiD· 1 shared Bert VogelsteiniD· 1 shared Bum Seok LeeiD· 1 shared Chetan BettegowdaiD· 1 shared Emma Gray· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersMolecular Biology

Phillip BuckhaultsORCID

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3 papers

Recent·Most cited

StarTrace: A Multiplex Organoid Avatar Drug Testing Platform for Personalized Medicine

Sana Khalili, Shrey Patel, Nidhi Patel, V. Moy, Sawyer Lyons, Emma Gray, Riley Brents, Carolyn E. Banister, Sidney E. Morrison, Phillip Buckhaults

StarTrace is a drug testing platform using patient-derived organoid avatars to rank drug responses and guide personalized therapy by multiplexing organoids with clonal barcoding.

BMC Cancer · Sep 15, 2026Peer-reviewedMolecular Biology

NXPE1 alters the sialoglycome by acetylating sialic acids in the human colon

Bum Seok Lee, Ashley L. Cook, Surojit Sur, Laura Dobbyn, Maria Popoli, Sana Khalili, Shibin Zhou, Chetan Bettegowda, Nickolas Papadopoulos, Kathy Gabrielson, Phillip Buckhaults, Bert Vogelstein, Kenneth W. Kinzler, Nicolas Wyhs

The paper identifies NXPE1 as a gene responsible for sialic acid O-acetylation in the human colon, linking it to mPAS staining differences through genetic and functional analyses.

Nature Communications · May 27, 2025Peer-reviewedGenetic & Genomic Medicine

Overcoming Cisplatin Resistance in TP53-null Colon Cancer Organoids

Sana Khalili, Paige Heine, Minou Khazan, Carolyn E. Banister, Sidney E. Morrison, Phillip Buckhaults

This study identifies gene knockouts in DNA repair pathways that re-sensitize TP53-null colon cancer organoids to cisplatin treatment.

bioRxiv · Feb 12, 2025 · PreprintMolecular Biology