Author

Jason G. Kerkvliet

South Dakota State UniversityORCID 0009-0002-8755-4059Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Approach:genetic perturbation / CRISPR· 2 Assay:bulk RNA-seq· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Assay:proteomics· 1

Frequent Co-Authors

Bijaya PradhaniD· 3 shared Natalie W. ThiexiD· 3 shared Adam D. HoppeiD· 2 shared Kevin N. WanniarachchiiD· 2 shared Amelia G. Lawver· 1 shared Astha NeupaneiD· 1 shared Bidhi KasuiD· 1 shared Jared W. Wollman· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersCell Biology

Bijaya PradhanORCID

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3 papers

Recent·Most cited

Cell BiologybioRxivPreprintSep 17, 2026

High-resolution CRISPR/Cas9 screens identify PAK2 as a suppressor of macrophage proliferation

Kevin N. Wanniarachchi, Astha Neupane, Bidhi Kasu…·Natalie W. Thiex

The paper uses CRISPR/Cas9 screens to identify PAK2 as a suppressor of macrophage proliferation in murine bone marrow-derived macrophages.

DOI 10.64898/2026.09.14.751564

mousegenetic perturbation / CRISPR

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Cell BiologyJournal of Lipid ResearchPeer-reviewedMay 7, 2026

Macrophage signaling and function are regulated by distinct sterol biochemistries

Jazmine D. W. Yaeger, Bijaya Pradhan, Jason G. Kerkvliet…·Kevin R. Francis

This study shows that altered sterol content in macrophages affects membrane dynamics and immune signaling, leading to impaired macropinocytosis and dysregulated vesicular sorting.

1 citation

mousebulk RNA-seq

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Cell BiologyMolecular Biology of the CellPeer-reviewedNov 6, 2024

Mannose receptor (MRC1) mediates uptake of dextran in macrophages via receptor-mediated endocytosis

Jared W. Wollman, Kevin N. Wanniarachchi, Bijaya Pradhan…·Natalie W. Thiex

This study identifies MRC1 as a key receptor for dextran uptake in macrophages via receptor-mediated endocytosis, distinguishing it from fluid-phase uptake mechanisms.

19 citations

mouseproteomics

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