Author

Mingrui Xu

Chinese Academy of SciencesORCID 0009-0002-9807-4376Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:experimental assay· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Jingjing WangiD· 3 shared Qingfeng WuiD· 2 shared Zhenhua CheniD· 2 shared Binshi Bo· 1 shared Biyu ReniD· 1 shared Bo WangiD· 1 shared Chan Xu· 1 shared Chuanyu LiuiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersNeuroscience

Jingjing WangORCID

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3 papers

Recent·Most cited

Identification of a neural basis for energy expenditure in the arcuate hypothalamus

Ting Wang, Shuping Han, Yaxin Wang, Yuxiao Li, Shuangfeng Zhang, Feipeng Zhu, Zhenhua Chen, Zhifang Xing, Yu Zheng Li, Jingjing Wang, Mingrui Xu, Qinghua Liu, Man Jiang, Xiaohong Xu, Xiangning Li, , Qingfeng Wu

This study identifies Crabp1 neurons in the arcuate hypothalamus as regulators of energy expenditure and body weight in mice through structural and functional analyses.

bioRxiv · Mar 11, 2025 · PreprintNeuroscience

Spatially resolved molecular and cellular atlas of the mouse brain

Lei Han, Zhen Liu, Zehua Jing, Yuxuan Liu, Huizhong Chang, Junjie Lei, Yujie Peng, Kexin Wang, Yuanfang Xu, Wei Liu, Zihan Wu, Qian Li, Xiaoxue Shi, Mingyuan Zheng, He Wang, , Sha Liao

The paper creates a high-resolution spatial transcriptomic atlas of the mouse brain using snRNA-seq and Stereo-seq, identifying new cell clusters, region-specific genes, and transcription factor regulons.

bioRxiv · Dec 3, 2023 · PreprintNeuroscience

Cascade Diversification Directs the Generation of Neuronal Diversity in Hypothalamus

Yu-Hong Zhang, Mingrui Xu, Xiang Shi, Xuelian Sun, Wenhui Mu, Haoda Wu, Jingjing Wang, Si Li, Pengfei Su, Ling Gong, Miao He, Mingze Yao, Qingfeng Wu

This study maps the developmental trajectory of hypothalamic neurons in mice using single-cell transcriptomics and lineage tracing, revealing a cascade diversification model for neuronal diversity.

Cell stem cell · Apr 21, 2021Peer-reviewedDevelopmental Biology