Miao He

The paper identifies two collateral-defined prefrontal-striatal subnetworks that differentially regulate initiation and approach vigor during appetitive goal pursuit.

The paper revisits the embryonic origins of forebrain oligodendrocytes using genetic fate mapping, finding that LGE/CGE-derived OLs dominate specific brain regions while MGE/POA-derived OLs contribute uniquely to the cortex.

The paper shows that GABAergic input from chandelier cells tunes the axon initial segment of pyramidal neurons to maintain homeostatic plasticity.

The paper uses genetic fate mapping in mice to show how direct and indirect neurogenesis contribute differently to the diversity and connectivity of glutamatergic projection neurons in the cerebral cortex.

This study maps the developmental trajectory of hypothalamic neurons in mice using single-cell transcriptomics and lineage tracing, revealing a cascade diversification model for neuronal diversity.

The paper identifies a brain circuit from the superior colliculus to the substantia nigra pars compacta that enhances appetitive locomotion during predatory hunting by modulating dopamine release.

The paper identifies two distinct neuron types in the lateral parabrachial nucleus that encode thermoregulation variables during heat defense.

The paper develops genetic tools to dissect glutamatergic neuron subpopulations and their developmental trajectories in the cerebral cortex.

Before eye opening, retinal and callosal activity regulates the density of chandelier cells in V1 to establish binocular vision.

This study identifies lineage programs in radial glial progenitors that generate striosome and matrix compartments through distinct intermediate progenitors, revealing their role in striatal circuit organization.

The paper identifies the insula-central amygdala circuit's role in avoidance behavior by showing its necessity and sufficiency for learning anticipatory avoidance of unpleasant tastants.

The paper identifies a specific class of central amygdala neurons that are essential for synaptic plasticity in the lateral amygdala during learning.

The paper identifies a transcriptional architecture that defines GABAergic neuron identity through combinatorial gene expression patterns.

This paper shows that chandelier cells selectively inhibit pyramidal neurons projecting to the basolateral amygdala, shaping communication between cortical networks.