Ana-Cristina Almansa-Garcia

This study shows that inhibiting VCP with ML240 prevents cone photoreceptor degeneration in a mouse model of achromatopsia without affecting rod photoreceptors.

This study shows that VCP inhibition with ML240 protects photoreceptors from hydroquinone-induced oxidative stress in a human iPSC-RPE/porcine neuroretina co-culture model.

This study evaluates three VCP-targeted therapies in a mouse model of retinitis pigmentosa, finding that nanocarrier-encapsulated ML240 provides the best protection against photoreceptor degeneration.

This study shows that the CFH Y402H polymorphism increases vulnerability of iPSC-RPE cells to Hydroquinone-induced oxidative stress, suggesting genetic risk predisposition rather than soluble FH effects.