Author

Merve Sen

University of TübingenORCID 0000-0002-5295-4493Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Blanca Arango‐GonzáleziD· 3 shared Marius UeffingiD· 3 shared Sylvia Bolz· 3 shared Ana-Cristina Almansa-GarciaiD· 2 shared Ellen KilgeriD· 2 shared Angela ArmentoiD· 1 shared Anne-Sophie Petremann-Dumé· 1 shared Anneli Vollert· 1 shared

Activity by Year

2020-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersNeuroscience

Blanca Arango‐GonzálezORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintJun 25, 2025

Ocular delivery of different VCP inhibitory formulations prevents retinal degeneration in rhodopsin 255 isoleucine deletion mice

Bowen Cao, Regine L. Mühlfriedel, Merve Sen…·Blanca Arango‐González

This study evaluates three VCP-targeted therapies in a mouse model of retinitis pigmentosa, finding that nanocarrier-encapsulated ML240 provides the best protection against photoreceptor degeneration.

DOI 10.1101/2025.06.25.661245

mouseexperimental assay

𝕏 PostBluesky

Cell BiologyFrontiers in ImmunologyPeer-reviewedFeb 6, 2025

The AMD-associated genetic polymorphism CFH Y402H confers vulnerability to Hydroquinone-induced stress in iPSC-RPE cells

Angela Armento, Inga Sonntag, Ana-Cristina Almansa-Garcia…·Marius Ueffing

This study shows that the CFH Y402H polymorphism increases vulnerability of iPSC-RPE cells to Hydroquinone-induced oxidative stress, suggesting genetic risk predisposition rather than soluble FH effects.

10 citationstop 2%

humanbulk RNA-seq

𝕏 PostBluesky

NeurosciencebioRxivPreprintNov 17, 2020

Inhibition of VCP preserves retinal structure and function in autosomal dominant retinal degeneration

Blanca Arango‐González, Merve Sen, Rosellina Guarascio…·Marius Ueffing

This study shows that inhibiting VCP activity rescues degenerating P23H rod cells and improves their function in retinal models of adRP.

11 citations

ratmouse

𝕏 PostBluesky