Author

Kaitlyn Gallagher

Vanderbilt UniversityORCID 0009-0003-0802-6424Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Assay:structural biology· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Walter J ChaziniD· 2 shared Alexandra M. BleeiD· 1 shared Areetha D’SouzaiD· 1 shared Christina R. TrolliD· 1 shared David CorteziD· 1 shared Hyun-Suk KimiD· 1 shared Jiyoung ParkiD· 1 shared Madison B. AdolphiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiophysics

Walter J ChazinORCID

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2 papers

Recent·Most cited

BiophysicsProceedings of the National Academy of SciencesPeer-reviewedMar 11, 2024

Structure of RADX and mechanism for regulation of RAD51 nucleofilaments

Swati Balakrishnan, Madison B. Adolph, Miaw-Sheue Tsai…·Walter Chazin

This paper investigates the structure and mechanism of RADX, a negative regulator of RAD51 nucleofilaments, showing it caps and restricts RAD51 filament growth to regulate replication fork reversal.

5 citations

structural biologyexperimental assay

𝕏 PostBluesky

Cancer BiologyNAR CancerPeer-reviewedJan 9, 2024

XPA tumor variants lead to defects in NER that sensitize cells to cisplatin

Alexandra M. Blee, Kaitlyn S Gallagher, Hyun-Suk Kim…·Walter J Chazin

This study identifies XPA tumor variants that impair NER, increasing cisplatin sensitivity, and provides mechanistic insights for variant effect prediction.

8 citations

humanproteomics

𝕏 PostBluesky