Author

Sizhe Tan

Imperial College LondonORCID 0009-0003-1292-8113Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Adrian Perez BarretoiD· 1 shared Aida Di Gregorio· 1 shared Ana LimaiD· 1 shared Karen H. VousdeniD· 1 shared Salvador Pérez-MonteroiD· 1 shared Sarah BowlingiD· 1 shared Shruthi KrishnaniD· 1 shared Tristan A. RodrígueziD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperDevelopmental Biology

Adrian Perez BarretoORCID

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1 paper

Recent·Most cited

Developmental BiologyScience AdvancesPeer-reviewedJul 9, 2025

Sensing of extracellular L-Proline availability by the integrated stress response determines the outcome of cell competition.

Shruthi Krishnan, Ana Lima, Sizhe Tan…·Tristan A. Rodríguez

The paper shows that winner cells in cell competition induce L-Proline uptake in loser cells, repressing the integrated stress response and leading to their elimination.

5 citations

mousebulk RNA-seq

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