BiochemistryJournal of the American Chemical SocietyPeer-reviewed
Discovery of novel covalent ligands with AlphaFold3
Yoav Shamir, Ronen Gabizon, Adi Rogel…·Nir London
This study demonstrates that AlphaFold3 can effectively discover novel covalent inhibitors for kinases through virtual screening, outperforming existing methods and validating predictions with co-crystallography.
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