This paper optimizes temporal interference stimulation (TIS) targeting in mice to reduce off-target effects while maintaining efficacy in the prefrontal cortex.

11 citationstop 2%

mouseelectronic health records

𝕏 PostBluesky

NeuroscienceMolecular PsychiatryPeer-reviewedJan 12, 2022

Inhibition of TRPV4 rescues circuit and social deficits unmasked by acute inflammatory response in a Shank3 mouse model of Autism

Stamatina Tzanoulinou, Stefano Musardo, Alessandro Contestabile…·Camilla Bellone

The paper shows that inhibiting TRPV4 rescues social and circuit deficits in Shank3 mutant mice induced by inflammation.

44 citationstop 4%

mouseexperimental assay

𝕏 PostBluesky

NeurosciencebioRxivPreprintApr 2, 2021

Optogenetic stimulation of BLA terminals in the BNST elicits long term synaptic plasticity and restores synaptic alterations induced by adolescent Shank3 downregulation

Christelle Glangetas, Alessandro Contestabile, Pedro Espinosa…·Camilla Bellone

This study investigates the role of Shank3 in anxiety behaviors by downregulating it in the BNST during adolescence and shows its impact on synaptic plasticity and anxiety-related behaviors.

DOI 10.1101/2021.04.02.438185

mouseexperimental assay

𝕏 PostBluesky