Daniel Razansky

This study identifies spatial and dynamic molecular heterogeneity in adult mouse brain pericytes across anatomical regions, vascular positions, aging, ischemia, and circadian phases.

The paper develops an automatic pipeline to measure scalp-to-region distances (SRD) in brain diseases and identifies distinct SRD alteration patterns in autism spectrum disorder, Alzheimer's disease, and Parkinson's disease.

This paper optimizes temporal interference stimulation (TIS) targeting in mice to reduce off-target effects while maintaining efficacy in the prefrontal cortex.

This paper maps α-synuclein pathology and dopaminergic degeneration in mice using multimodal imaging and microscopy, showing spread along the nigrostriatal pathway and microstructural changes.

This paper introduces an optical clearing method using tartrazine to enable non-invasive OCTA imaging of the mouse cortex through intact skull and scalp.

SALM uses deep learning to convert motion-blurred streaks into high-resolution brain imaging, reducing reconstruction time and enabling scalable, cross-platform applications.

Event2Flow uses event-based sensors to efficiently map blood flow in mice, enabling noninvasive vascular and brain imaging with reduced data and computational demands.

This study identifies reprogrammed neutrophils with impaired transit mechanics as a driver of multi-organ capillary stalling after stroke, showing therapeutic potential through Fgr inhibition.

This paper introduces a data-driven method to retrieve effective point spread functions for super-resolution optoacoustic imaging, improving resolution and reducing artifacts in under-sampled conditions.

The paper shows pial collaterals propagate neurovascular signals between cortical territories, synchronizing blood flow responses beyond activated areas.

This paper develops a wireless system for simultaneous EEG and fMRI recording, demonstrating its ability to capture neurovascular coupling in the somatosensory cortex.

The paper develops OMNIMap to analyze cerebrovascular flow and identifies flow topology as a marker of capillary vulnerability after stroke.

The paper examines reduced SV2A levels in AD brain tissue and extracellular vesicles, linking them to amyloid-β, tau, and synaptic markers.

This paper develops a new imaging technique to study brain perfusion in mice during ischemic stroke, showing its ability to map vascular changes and assess therapeutic effects.

This study introduces Bessel beam optical coherence microscopy to assess cerebrovascular network morphology and function in mice at high resolution and across multiple scales.

Pia-FLOW maps hemodynamic properties of the murine pial vascular network and shows its unified response to arterial occlusion.

This study finds no difference in hippocampal mGluR5 levels between Alzheimer's and control brains, but shows amyloid and tau have opposing effects on mGluR5 in controls.

The paper uses multimodal imaging to assess spinal cord oxygenation and vascular changes in a PD mouse model, finding reduced oxygen saturation but no vascular impairment or atrophy.

The paper uses PET and MSOT to observe hypoxia and increased spinal cord metabolism in tMCAO mice compared to sham-operated mice.

The paper introduces a semi-automated toolkit to estimate stroke infarct volumes in rodents using MRI and histological sections, showing high correlation between the two methods.

The paper visualizes alpha-synuclein inclusions and iron deposition in M83 mouse models of Parkinson's disease using in vivo imaging and ex vivo validation techniques.

The paper develops an automatic pipeline for analyzing skull thickness and scalp-to-cortex distance from MRI data and shows age and sex-related changes in these metrics in elderly individuals.

This paper demonstrates noninvasive transcranial MSOT angiography in a human volunteer and validates its anatomical alignment with MRI.

This study shows that tonic and burst firing patterns of the locus coeruleus modulate brain activity and dynamics in mice through distinct mechanisms.

This paper develops a multimodal imaging approach using TROPUS to assess NAFLD in mice, enabling early detection of fat accumulation and liver damage through optical and acoustic contrasts.

The paper investigates AQP4 distribution and depolarization in tau and amyloid-beta pathologies using mouse models and imaging techniques.

This paper demonstrates non-invasive whole brain imaging of tau deposits using vMSOT and PBB5 probe in P301L mice, showing specific binding and retention in tau-laden regions.

This study uses a hybrid imaging platform to simultaneously observe hemodynamic and calcium responses in mice brains during sensory stimulation, revealing their complex interplay.

This paper characterizes CRANAD-2 for detecting amyloid-beta deposits in Alzheimer's mouse models using multi-spectral optoacoustic tomography and fluorescence imaging.

This study uses optogenetics and fMRI to show that D1 and D2 MSNs in the striatum differentially activate brain regions beyond the basal ganglia, revealing complex functional interactions.