Stoichiometric m6A regulation of YY1 orchestrates the metabolic switch during cardiac development
Shunyao Lei, Harshi Gangrade, Sheetal Bajpayi, Qingqing Gong, Courtney Hall, Edwin Jong-woo Yoo, Simone Sidoli, Nanami Senoo, Konstantinos Boulias, Steven Michael Claypool, Winston Timp, Emmanouil Tampakakis
The paper identifies a bimodal m6A code in cardiac development, showing how m6A stoichiometry and context regulate metabolic switches and gene expression.
bioRxiv · Sep 28, 2026 · PreprintDevelopmental Biology