Giulia Parodi

This study develops human neurospheroids to model cortical complexity, finding that three-dimensionality and modularity enhance network activity richness and complexity.

This study compares three metabolic stress models on human-derived neuronal networks, showing distinct effects on activity and viability, with limited recovery after reoxygenation.

This study investigates SCN1A mutations in excitatory neuronal networks derived from patient hiPSCs, revealing mutation-specific phenotypes that correlate with clinical outcomes and drug responses.

The paper benchmarks MEA recordings from healthy hiPSC-derived neuronal networks to establish standards for experimental design and analysis, showing MEAs are robust for disease-phenotyping and drug discovery.