Author

Ryen Hazzard

University of Wisconsin–MadisonORCID 0009-0003-3348-3547Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 2 Approach:experimental assay· 2 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1

Frequent Co-Authors

Andrew Q. RashoffiD· 2 shared Peter W. LewisiD· 2 shared Abby J. Ruffridge· 1 shared Ali Torhorst· 1 shared Benjamin A. GarciaiD· 1 shared Charalambos S. RoussosiD· 1 shared Elizabeth G. Poulsen PorteriD· 1 shared F Javier deHaro-ArbonaiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersBiochemistry

Andrew Q. RashoffORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintJul 22, 2026

EZH2 Serine 21 Phosphorylation Restrains Compact-State PRC2 Activation and H3K27me3 Propagation

Andrew Q. Rashoff, Mark N. Matyas, Elizabeth G. Poulsen Porter…·Peter W. Lewis

This study identifies EZH2 serine 21 phosphorylation as a mechanism that limits PRC2 activation and H3K27me3 propagation, affecting developmental processes in mesenchymal progenitor cells.

DOI 10.64898/2026.06.02.729660

humanChIP-seq

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Molecular BiologyScience AdvancesPeer-reviewedJun 19, 2026

Pioneer-factor activity requires stable chromatin occupancy mediated by both sequence-specific binding and disordered protein domains

Meghan M. Freund, F Javier deHaro-Arbona, Sarah Baloul…·Melissa M. Harrison

This study identifies that both sequence-specific DNA binding and disordered protein domains are required for pioneer-factor chromatin occupancy, with mitotic retention relying only on DNA binding.

4 citationstop 2%

ChIP-seqexperimental assay

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