Author

Meghan M. Freund

University of Wisconsin–MadisonORCID 0000-0001-9608-5042Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 1 Approach:experimental assay· 1

Frequent Co-Authors

Abby J. Ruffridge· 1 shared Ali Torhorst· 1 shared Andrew Q. RashoffiD· 1 shared Charalambos S. RoussosiD· 1 shared F Javier deHaro-ArbonaiD· 1 shared Melissa M. HarrisoniD· 1 shared Peter W. LewisiD· 1 shared Ryen HazzardiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Abby J. Ruffridge

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1 paper

Recent·Most cited

Molecular BiologyScience AdvancesPeer-reviewedJun 19, 2026

Pioneer-factor activity requires stable chromatin occupancy mediated by both sequence-specific binding and disordered protein domains

Meghan M. Freund, F Javier deHaro-Arbona, Sarah Baloul…·Melissa M. Harrison

This study identifies that both sequence-specific DNA binding and disordered protein domains are required for pioneer-factor chromatin occupancy, with mitotic retention relying only on DNA binding.

4 citationstop 2%

ChIP-seqexperimental assay

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