Ying Guan

This study shows nicotine reduces α-synuclein pathology and behavioral deficits in mice induced by human α-synuclein pre-formed fibrils.

This study identifies function-specific sites in nAChR subunits using evolutionary analysis and spatial modeling, showing their roles in ligand binding and conformational changes.

This study develops a DNA-based modulator to replace growth factors in culturing human neural progenitor cells, enabling long-term propagation and neurogenesis.