Zhouhai Zhu

Nicotine Ameliorates α-synuclein Pre-formed Fibril-Induced Behavioral Deficits and Pathological Features in Mice

This study shows nicotine reduces α-synuclein pathology and behavioral deficits in mice induced by human α-synuclein pre-formed fibrils.

An automated microfluidic platform for toxicity testing based on Caenorhabditis elegans

This paper introduces an automated microfluidic platform using C. elegans to assess chemical toxicity, showing it can evaluate general and developmental impacts of chemicals.

Identification of the potential function-specific sites in subunits of vertebrate neuronal nicotinic acetylcholine receptors

This study identifies function-specific sites in nAChR subunits using evolutionary analysis and spatial modeling, showing their roles in ligand binding and conformational changes.

Analyzing the Involvement of Cholinesterases in the Immune Landscape of Lung Adenocarcinoma and Their Prognostic Values

The paper identifies AChE and BChE as prognostic markers in LUAD, showing their association with immune landscape and prognosis in different patient subgroups.

Neuroprotective Effects of Bioactive Molecules Derived from Tobacco as Potential Therapeutic Candidates for Alzheimer Disease

The paper identifies three tobacco-derived compounds with neuroprotective effects against Alzheimer's disease using a genetic engineering approach with neural progenitor cells.

Development of Synthetic Modulator Enabling Long-Term Propagation and Neurogenesis of Human-Derived Neural Progenitor Cells

This study develops a DNA-based modulator to replace growth factors in culturing human neural progenitor cells, enabling long-term propagation and neurogenesis.