Author

Haodong Guo

Center for Life SciencesORCID 0009-0003-3686-6391Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Boyi CheniD· 1 shared Chun Li· 1 shared Hongyang Guo· 1 shared Lei LüiD· 1 shared Qiaoling Shangguan· 1 shared Shangxun Zhao· 1 shared Shaopeng Sun· 1 shared Shuai XuiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Boyi ChenORCID

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1 paper

Recent·Most cited

BiochemistryNature Chemical BiologyPeer-reviewedOct 29, 2026

In vivo-compatible spatial multi-omics via hydrogen peroxide-independent APEX2 labeling

Boyi Chen, Hongyang Guo, Zhijian Yan…·Wei Qin

This paper introduces Hi-APEX, a H2O2-independent APEX2 variant for in vivo spatial multi-omics, showing improved performance in capturing redox-sensitive processes and enabling in vivo applications.

2 citationstop 4%

mousespatial transcriptomics

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