Author

Chun Li

Chinese Academy of Sciences

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Biochemistry· 2 Bioinformatics· 1 Cancer Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell type annotation· 3 Research Focus:drug response / drug discovery· 3 Organism:human· 2 Organism:mouse· 2 Research Focus:protein folding & dynamics· 2 Assay:proteomics· 2 Assay:ATAC-seq· 1

Frequent Co-Authors

Amen Shamin· 1 shared Ananya ChoudhuryiD· 1 shared Benito F. Buksh· 1 shared Boyi CheniD· 1 shared Cheng LuoiD· 1 shared David Fernandez· 1 shared David W. C. MacMillaniD· 1 shared Effrosyni Antonopoulou· 1 shared

Activity by Year

2023-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 9 mutual co-author links

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1 shared paperCancer Biology

Amen Shamin

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Author profile →

5 papers

Recent·Most cited

In vivo-compatible spatial multi-omics via hydrogen peroxide-independent APEX2 labeling

Boyi Chen, Hongyang Guo, Zhijian Yan, Wenjie Lu, Chun Li, Shuai Xu, Yanling Zhang, Haodong Guo, Shaopeng Sun, Xuege Sun, Shangxun Zhao, Qiaoling Shangguan, Yidong Chen, Lei Lü, Zhaofa Wu, , Wei Qin

This paper introduces Hi-APEX, a H2O2-independent APEX2 variant for in vivo spatial multi-omics, showing improved performance in capturing redox-sensitive processes and enabling in vivo applications.

Nature Chemical Biology · Oct 29, 2026Peer-reviewedBiochemistry

μMap-uAA: Photocatalytic proximity labeling targeted with single-residue precision

Min Sun Kang, Chun Li, Benito F. Buksh, David Fernandez, David W. C. MacMillan

The paper introduces Map-uAA, a method for mapping protein microenvironments with residue-level precision using photocatalytic proximity labeling.

bioRxiv · Aug 6, 2026 · PreprintBiochemistry

Inhibiting RhoA Activation via GDP-state Stabilization to Relieve Heart Failure

Mengzhu Xue, Yingquan Liang, Zhen Yuan, Xiangning Liu, Longfeng Chang, Yongzhi Wang, Peijia Xu, Tingting Zhang, Hewei Jiang, Zijie Zhao, Jingqiu Liu, Shanshan Ruan, Tianyu Ye, Xuelian Pang, 梅文一, , Honglin Li

This study identifies a compound that inhibits RhoA activation by stabilizing its GDP state, reducing myocardial remodeling and fibrosis in heart failure models.

Circulation Research · Mar 20, 2026Peer-reviewedPharmacology & Toxicology

WSB-1 regulates DNA repair and the response to DNA damage response inhibitors in breast cancer

Effrosyni Antonopoulou, Chun Li, Amen Shamin, Scott Taylor, Flore-Anne Poujade, Michael Lind, Rajarshi Roy, Ananya Choudhury, Isabel M. Pires

This study shows WSB-1 regulates DNA repair and enhances sensitivity to DNA damage response inhibitors in breast cancer.

bioRxiv · Aug 27, 2025 · PreprintCancer Biology

MINE is a method for detecting spatial density of regulatory chromatin interactions based on a MultI-modal NEtwork

Haiyan Gong, Minghong Li, Mengdie Ji, Xiaotong Zhang, Zan Yuan, Sichen Zhang, Yi Yang, Chun Li, Yang Chen

The paper introduces MINE, a toolkit to detect and analyze spatial density of regulatory chromatin interactions using Hi-C, ATAC-seq, and histone ChIP-seq data.

Cell Reports Methods · Jan 1, 2023Peer-reviewedBioinformatics