Author

Nickolas P. Fisher

Northwestern UniversityORCID 0000-0002-8574-7503Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:benchmarking· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1 Research Focus:sequence-to-function modeling· 1

Frequent Co-Authors

Neil L. KelleheriD· 2 shared Taojunfeng SuiD· 2 shared Alexander S LeeiD· 1 shared Bria GrahamiD· 1 shared Catherine A. MusselmaniD· 1 shared Hailey F. TayloriD· 1 shared Harrison A. FuchsiD· 1 shared Jared O. KafaderiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBioinformatics

Neil L. KelleherORCID

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintJun 3, 2026

Deep Proteoform Sequencing with Top-Down Direct Mass Technology

Kenneth R. Durbin, Taojunfeng Su, Ryan T. Fellers…·Neil L. Kelleher

This paper introduces a top-down mass spectrometry workflow with DMTm technology and a new software platform to achieve deeper proteoform sequencing and improved sequence coverage.

DOI 10.64898/2026.05.29.728917

proteomicsexperimental assay

𝕏 PostBluesky

BiochemistryACS Central SciencePeer-reviewedFeb 5, 2026

Direct Readout of Multivalent Chromatin Reader-Nucleosome Interactions by Nucleosome Mass Spectrometry

Alexander S Lee, Nickolas P. Fisher, Matthew R. Marunde…·Neil L. Kelleher

This paper introduces Nuc-MS, a method to directly analyze chromatin reader-nucleosome interactions by disassembling complexes and identifying histone proteoforms involved in binding.

2 citations

humanChIP-seq

𝕏 PostBluesky