Author

Boris Taillefer

Centre National de la Recherche ScientifiqueORCID 0009-0003-3949-751XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Organism:E. coli· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1

Frequent Co-Authors

Eric CascalèsiD· 2 shared Agathe Brault· 1 shared Alain SarniguetiD· 1 shared Florian Schattenberg· 1 shared Jonas B. DesjardinsiD· 1 shared Susann MülleriD· 1 shared Thierry DoaniD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

7 top collaborators · 8 mutual co-author links

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2 shared papersMicrobiology

Eric CascalèsORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

MicrobiologybioRxivPreprintJul 16, 2026

A conserved Rhs module associated with the type VI secretion system facilitates effector innovation and immunity acquisition for ecological adaptation of Stenotrophomonas species

Boris Taillefer, Agathe Brault, Alain Sarniguet

This study identifies a conserved Rhs module in Stenotrophomonas species linked to T6SS effector innovation and immunity, enabling ecological adaptation in saline niches.

DOI 10.64898/2026.07.13.738213

bacteria (other)proteomics

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MicrobiologybioRxivPreprintFeb 11, 2025

Type VI secretion phenotypic heterogeneity ensures trade-off between antibacterial activity and resistance in Enteroaggregative E. coli

Boris Taillefer, Florian Schattenberg, Thierry Doan…·Eric Cascalès

This study shows that Enteroaggregative E. coli exhibits T6SS phenotypic heterogeneity, enabling a trade-off between antibacterial activity and resistance in mixed microbial environments.

3 citations

E. coliproteomics

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MicrobiologybioRxivPreprintFeb 8, 2025

Molecular bases for the loss of type VI secretion system activity during enteroaggregative E. coli experimental evolution

Boris Taillefer, Jonas B. Desjardins, Eric Cascalès

This study uses experimental evolution to show that T6SS activity is lost in EAEC when grown with immune cells, identifying mutations and a novel RfaH-dependent regulatory mechanism.

3 citations

E. coliwhole-genome sequencing

𝕏 PostBluesky