Yuxuan Liu

This study analyzes genomes and transcriptomes of deep-sea anemones to reveal evolutionary patterns and adaptive strategies, finding repeated gene loss and molecular innovations in deep-sea species.

This paper introduces GO-CRE, a method for designing cell-type-specific cis-regulatory elements by reconstructing sequence-grammar trajectories and using reinforcement learning with predictor guidance.

This study creates a single-cell spatial transcriptomic atlas of the human cortex, revealing gene expression patterns, aging effects, and disease associations across layers and species.

BrainBeacon is a cross-species foundation model for whole-brain spatial transcriptomics that enables cross-species alignment and uncovers spatial regulatory mechanisms of aging.

HemaCisDB is a database that characterizes cis-regulatory elements in hematopoietic malignancies using ATAC-seq, DNase-seq, and H3K27ac ChIP-seq data.