Jing Yang

OmniSyn generates and optimizes target-specific molecules with synthesis traces using a sequence-conditioned LLM, achieving state-of-the-art performance on drug discovery benchmarks.

FlexiTAC generates controllable PROTAC linkers using a Bayesian flow network, improving validity and pose quality over existing methods.

This study shows that structural brain networks influence individual brain atrophy patterns after stroke, with atrophy spreading through the network from the initial lesion.