Author

Katherine F. Donovan

Broad InstituteORCID 0009-0003-6657-500XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Amy B. GoodaleiD· 1 shared Christine StrandiD· 1 shared David E. RootiD· 1 shared Emma W VaimbergiD· 1 shared Federica PiccioniiD· 1 shared John G. DoenchiD· 1 shared Kendall R Sanson· 1 shared Meagan E. SullenderiD· 1 shared

Activity by Year

2018-2018 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperGenomics

Amy B. GoodaleORCID

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1 paper

Recent·Most cited

GenomicsNature CommunicationsPeer-reviewedDec 17, 2018

Up, down, and out: optimized libraries for CRISPRa, CRISPRi, and CRISPR-knockout genetic screens

Kendall R Sanson, Ruth E. Hanna, Mudra Hegde…·John G. Doench

The paper evaluates and introduces optimized CRISPR libraries for knockout, interference, and activation screens, showing improved performance in gene function interrogation.

1,043 citationstop 1%

CRISPR screenexperimental assay

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