PhysiologybioRxivPreprint
Rapid onset fibrotic remodeling and ventricular dysfunction induced by phenylephrine involve targeted reprogramming of myocyte and fibroblast transcriptomes
Todd Haswell Kimball, Tatiana Gromova, Natalie Gehred…·Thomas M. Vondriska
This study shows that phenylephrine induces rapid fibrotic remodeling and ventricular dysfunction in mice through myocyte and fibroblast transcriptome reprogramming.
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