Author
University of California, Los AngelesORCID 0000-0002-7815-4881Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
4 papers
Recent·Most cited
Mahmoud H. Elbatreek, Zhen Li, Xiaoman Yu…·David J. Lefer
This study shows low-dose GLP-1RA therapy improves cardiac and hepatic function in HFpEF without weight loss, through mechanisms like reduced fibrosis and lipid accumulation.
Zhen Li, Kyle Brian LaPenna, Natalie Gehred…·David J. Lefer
This study identifies dysregulated nitrosylation dynamics in HFpEF patients and ZSF1 obese rats, showing elevated nitrosative stress markers and impaired trans- and de-nitrosylase activity.
Jake E. Doiron, Mahmoud H. Elbatreek, Huijing Xia…·David J. Lefer
This study shows H2S deficiency in HFpEF patients and models, and that H2S supplementation or combination with GLP-1/glucagon agonists improves HFpEF outcomes.
Todd Haswell Kimball, Tatiana Gromova, Natalie Gehred…·Thomas M. Vondriska
This study shows that phenylephrine induces rapid fibrotic remodeling and ventricular dysfunction in mice through myocyte and fibroblast transcriptome reprogramming.