Zach Fyke

This study shows chronic stress increases microglial complexity in the anterior piriform cortex, correlating with odor avoidance behavior in mice.

This study shows that TMEM16B reduces sensory representation density in OSNs, enhancing sparsity and improving olfactory-guided behaviors.

This study shows that NtBuHA reduces neuroinflammation and seizures in a Cln1-/- mouse model of CLN1 Batten Disease.

This study shows that loss of PPT1, a depalmitoylating enzyme, leads to exaggerated synaptic upscaling and neuroinflammation in a lysosomal storage disease.