Rushika Raval

C19 trityl and silyl andrographolide analogs exhibit in vitro anticancer activity in murine cancer models

This study evaluates trityl and silyl ether analogs of andrographolide in murine cancer cell lines, finding potent anticancer activity and mechanisms involving apoptosis and Wnt1/β-catenin signaling.

Anticancer synthetic arylsulfonamides with Wnt1-modulating activity

The paper evaluates analogs of MSAB, a Wnt1/{beta}-catenin inhibitor, to determine how ester substitutions affect antiproliferative activity in cancer cell lines.

Direct expression of CPT1a enables a high throughput platform for the discovery of CPT1a modulators

The paper develops a high-throughput platform using catalytically active CPT1a to screen for modulators, validated with known inhibitors and a library of small molecules.