A family of bacterial Josephin-like deubiquitinases with an unusual cleavage mode
Thomas Hermanns, Susanne Kolek, Matthias Uthoff, Richard A. de Heiden, Monique P. C. Mulder, Ulrich Baumann, Kay Hofmann
The paper identifies a new family of bacterial deubiquitinases that cleave ubiquitin before the C-terminal diGly motif, truncating the modifier and leaving a remnant on the substrate.
Molecular Cell · Mar 1, 2025Peer-reviewedBiochemistry