Monique P. C. Mulder

This study identifies a novel E3 ligase secreted by Pseudomonas aeruginosa that regulates virulence through ubiquitin modification.

The paper identifies a new family of bacterial deubiquitinases that cleave ubiquitin before the C-terminal diGly motif, truncating the modifier and leaving a remnant on the substrate.

This paper determines the crystal structure of KLHL3 in complex with a WNK3 peptide, revealing structural features and phosphorylation-dependent regulation of WNK3 binding.