NeuroscienceNeuropsychopharmacologyPeer-reviewed
Interruption of Continuous Opioid Exposure Exacerbates Drug-Evoked Adaptations in the Mesolimbic Dopamine System
Emilia M. Lefevre, Marc T. Pisansky, Carlee Toddes…·Patrick E. Rothwell
This study shows that interrupting continuous opioid exposure increases drug-evoked adaptations in the mesolimbic dopamine system, leading to greater behavioral and transcriptional changes.
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