Thomas J. Y. Kono

SC-BIG improves single-cell SNV detection by integrating bulk sequencing data, outperforming existing methods in simulated scenarios.

The paper presents a high-quality whole genome assembly and annotation of Northern Wild Rice, revealing a whole genome duplication event in the Zizania genus.

This study shows that interrupting continuous opioid exposure increases drug-evoked adaptations in the mesolimbic dopamine system, leading to greater behavioral and transcriptional changes.

The paper identifies and analyzes deleterious SNPs in a barley breeding population, showing they decrease in frequency over breeding cycles and are less common in high-yielding lines.

This paper presents the genome of the zebra mussel, Dreissena polymorpha, providing insights into its invasive success and creating a resource for invasive species research.

The paper evaluates seven comparative genomic methods for predicting deleterious variants in Arabidopsis thaliana and finds their relative performance varies across species.

This study shows that RNA storage methods like RNAlater and flash freezing affect gene expression, with RNAlater causing biased results in RNAseq experiments.

The paper identifies thousands of tandem duplicate genes in maize, showing they are abundant and date to two distinct periods of genomic instability.