Author

Ricardo Scheufen Tieghi

University of North Carolina at Chapel HillORCID 0009-0004-0763-6412Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:statistical model· 1

Frequent Co-Authors

Alexander TropshaiD· 1 shared Alexey V. ZakharoviD· 1 shared Anton SimeonoviD· 1 shared Dorjbal G. Dorjsuren· 1 shared Eugene N. MuratoviD· 1 shared Jon-Michael T. BeasleyiD· 1 shared Marielle K. RathiD· 1 shared Sankalp JainiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperBioinformatics

Alexander TropshaORCID

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1 paper

Recent·Most cited

Breaking the Phalanx: Overcoming Bacterial Drug Resistance with Quorum Sensing Inhibitors that Enhance Therapeutic Activity of Antibiotics

Jon-Michael T. Beasley, Dorjbal G. Dorjsuren, Sankalp Jain, Marielle K. Rath, Ricardo Scheufen Tieghi, Alexander Tropsha, Anton Simeonov, Alexey V. Zakharov, Eugene N. Muratov

This study identifies synergistic combinations of quorum-sensing inhibitors and antibiotics to combat antibiotic-resistant bacteria, finding that piperacillin with ketoprofen, indomethacin, and piroxicam shows broad antimicrobial action.

bioRxiv · Jan 17, 2025 · PreprintBioinformatics