Author

Alexandra Typou

Centre National de la Recherche ScientifiqueORCID 0009-0004-1334-6796Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:proteomics· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Apostolos AvgeropoulosiD· 1 shared Arnaud MonteiliD· 1 shared Brandon B. HolmesiD· 1 shared Christos G. GkogkasiD· 1 shared Daohong ZhouiD· 1 shared Dimitrios MoschovasiD· 1 shared Donard S. DwyeriD· 1 shared Elpida StatoullaiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperNeuroscience

Apostolos AvgeropoulosORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintOct 9, 2026

An AI-Enabled Translational Drug Discovery Framework for NALCN Channelopathy: From High-Throughput Screening to Therapeutic Candidate

Nattaya Thongsepee, Jeremy A. Tanner, Srikanth R. Polusani…·Yaxia Yuan

This paper develops an AI-driven drug discovery framework for NALCN channelopathy, identifying aprepitant as a lead therapeutic candidate through HTS, structural modeling, and experimental validation.

DOI 10.64898/2026.10.08.757476

humanmouse

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NeuroscienceBiological Psychiatry Global Open SciencePeer-reviewedNov 8, 2024

GABA/Glutamate neuron differentiation imbalance and increased AKT/mTOR signalling in CNTNAP2-/-cerebral organoids.

Kleanthi Chalkiadaki, Elpida Statoulla, Maria Zafeiri…·Christos G. Gkogkas

This study uses cerebral organoids to show that CNTNAP2 loss causes imbalanced GABA/glutamate neuron differentiation and increased AKT/mTOR signaling, linked to ASD pathophysiology.

12 citations

humanbulk RNA-seq

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