Astrid Hofman

This study creates a multi-organ single-cell atlas of systemic sclerosis to identify shared and tissue-specific transcriptional programs and potential therapeutic targets.

This study compares two culture systems for mouse living myocardial slices, finding the biomimetic system provides better viability, structure, and function for cardiac fibrosis research.

This study characterizes PDE4B expression in systemic sclerosis (SSc) tissues, showing dysregulation in immune cells and protein enrichment in activated fibroblasts, supporting PDE4B as a therapeutic target.