Author

Blaž Burja

University of Zurich

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:clustering· 1

Frequent Co-Authors

Oliver DistleriD· 3 shared Caroline OspeltiD· 2 shared Mark D. RobinsoniD· 2 shared Miranda HoutmaniD· 2 shared Mojca Frank‐BertonceljiD· 2 shared Nadja Ižanc· 2 shared Reto GerberiD· 2 shared Sam G. Edalat· 2 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersMolecular Biology

Oliver DistlerORCID

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Author profile →

3 papers

Recent·Most cited

Compartmental Profiling of PDE4B in Systemic Sclerosis

Astrid Hofman, Pietro Bearzi, Sara Burckhardt, Maryam Asadikorayam, Andrea Laimbacher, Cristian Iperi, Muriel Elhaï, Cosimo Bruni, Flurin Sturzenegger, Shervin Assassi, Laura Much, Anna‐Maria Hoffmann‐Vold, Blaž Burja, Helen C. Jarnigan, Michael L. Whitfield, , Oliver Distler

This study characterizes PDE4B expression in systemic sclerosis (SSc) tissues, showing dysregulation in immune cells and protein enrichment in activated fibroblasts, supporting PDE4B as a therapeutic target.

bioRxiv · Jul 28, 2026 · PreprintMolecular Biology

Synovial fibroblast niche shapes the efficacy - safety dynamics of JAK inhibition in rheumatoid arthritis

Ana Županič, Sam G. Edalat, Blaž Burja, Miriam Paulina Busch, Tadeja Kuret, Nadja Ižanc, R. S. Zingg, Laura M. Merlo Pich, Snežna Sodin‐Šemrl, Oliver Distler, Miranda Houtman, Caroline Ospelt, Reto Gerber, Mark D. Robinson, Mojca Frank‐Bertoncelj

This study identifies synovial fibroblasts as key targets of JAK inhibition in RA and reveals cytokine- and drug-driven mechanisms affecting JAKi efficacy and safety.

bioRxiv · Mar 25, 2026 · PreprintMolecular Biology

A reference single-cell map of freshly dissociated human synovium in inflammatory arthritis with an optimized dissociation protocol for prospective synovial biopsy collection

Sam G. Edalat, Reto Gerber, Miranda Houtman, Janine Lückgen, Rui Lourenço Teixeira, Maria Del Pilar Palacios Cisneros, Tamara Pfanner, Tadeja Kuret, Nadja Ižanc, Raphael Micheroli, Joaquim Polido Pereira, Fernando Saraiva, Swathi Lingam, Kristina Bürki, Blaž Burja, , Mojca Frank‐Bertoncelj

The paper optimizes a dissociation protocol for fresh synovial biopsies and creates a single-cell reference map of human synovium in inflammatory arthritis, revealing new cell types and functions.

iScience · Apr 10, 2024Peer-reviewedGenomics