Author

Yaoqin Zhao

Chinese Academy of SciencesORCID 0009-0004-1645-6165Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Approach:genetic perturbation / CRISPR· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Chengxiang XiaiD· 3 shared Fangxiao HuiD· 3 shared Jinyong WangiD· 3 shared Leqiang ZhangiD· 3 shared Qitong WengiD· 3 shared Tongjie WangiD· 3 shared Yiyuan SheniD· 3 shared Yunqing LiniD· 3 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

Chengxiang XiaORCID

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3 papers

Recent·Most cited

Cancer BiologyJournal for ImmunoTherapy of CancerPeer-reviewedSep 1, 2025

CD33KO-CD33-mesothelin loop CAR design avoids fratricide and improves efficacy of iNK cells against acute myeloid leukemia

Yao Wang, Xiujuan Zheng, Zhiqian Wang…·Jinyong Wang

This study designs a CD33-mesothelin loop CAR to enhance iNK cell efficacy against AML by avoiding fratricide and improving cytotoxicity.

6 citations

𝕏 PostBluesky

ImmunologybioRxivPreprintJul 11, 2025

Pluripotent stem cell-derived siTNK cells attack tumors via a synthetic CD8-CD28 TCR complex

Xiujuan Zheng, Fan Zhang, Yunqing Lin…·Minghan Zhang

The paper generates siTNK cells from hPSCs using a synthetic TCR complex, showing tumor-specific cytotoxicity and anti-tumor activity in xenograft models.

DOI 10.1101/2025.07.11.663392

𝕏 PostBluesky

Cancer BiologyJournal of Hematology & OncologyPeer-reviewedMay 19, 2025

Engineered CRO-CD7 CAR-NK cells derived from pluripotent stem cells avoid fratricide and efficiently suppress human T-cell malignancies

Yunqing Lin, Ziyun Xiao, Fangxiao Hu…·Jinyong Wang

This study generates CD7 CAR-NK cells from pluripotent stem cells that avoid fratricide and effectively suppress T-cell malignancies in xenograft models.

16 citationstop 2%

humanexperimental assay

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