Shubham Singh

LipidCruncher processes, visualizes, and analyzes lipidomic data with quality controls, enabling efficient and rigorous analysis of lipid profiles.

The paper identifies plasma lipidome changes in FTD carriers, finding specific lipid alterations linked to genetic subtypes and disease severity.

This study identifies PLD3 and PLD4 as enzymes synthesizing S,S-BMP, a lysosomal phospholipid critical for lipid degradation and brain health.

This study shows that loss of ABHD12 enzymatic activity increases phagocytosis in cerebellar microglia, leading to neuroinflammation in a mouse model of PHARC.